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Cat#：163P03
序列（三字母）：H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH trifluoroacetate salt
序列（單字母）：MAPRGFSCLLLLTGEIDLPVKRRA
類似名：S14G-Humanin (human)
分子式：C???H???N??O??S?
分子量：2657.25
CAS#：330936-70-4
合成方法：Synthetic
存儲條件：-20 ± 5 °C
應用：Alzheimer′s Disease
描述：S14G-Humanin (HNG) is a more potent neuroprotective factor than native humanin. In middle-aged APPswe/PS1dE9 mice, the mutant peptide improved cognitive deficits and reduced amyloid pathology. S14G-Humanin inhibited Aβ 1-42 fibril formation, disaggregates preformed fibrils, and protects against Abeta-induced cytotoxicity in vitro.